Endocrine Abstracts

Introduction: Hyponatremia is a frequently encountered electrolyte disturbance in clinical practice. The etiology should be searched and revisited properly to be able to guide the appropriate management.Case-report: A 39-years old woman with type 1. diabetes since childhood, after combined pancreas-kidney transplantation with good stable functions of both organs, was admitted to our internal ward for overall fatigue, fever, unspecific abdominal pain with...

Introduction: Metformin is recommended as the first-line pharmacological agent for patients with diabetes mellitus type 2. Its most feared adverse effect is the metformin-associated lactic acidosis (MALA), which appears rarely, but the mortality risk reaches almost 50 percent. This case report describes a story of a severely metformin intoxicated patient with several rare complications and uneven outcome.Case-report: A 74-year-old man was found at home, ...

Introduction: Lymphomas account for <5% of thyroid malignancies. The vast majority of them are non-Hodgkin’s lymphomas (NHL), especially mucosa-associated lymphoid tissue lymphomas (MALT) and diffuse large B-cell lymphomas (DLBCL). However, Hodgkin’s lymphoma affecting thyroid gland is very rare. Worldwide has been reported <50 cases so far and we describe another one.Case report: A 22-year-old woman was referred to our department of en...

Introduction: The diagnostic procedure of primary aldosteronism (PA) includes one of four confirmatory tests, of which the saline suppression test (SST) seems to be the most convenient one. Current guidelines recommend SST to be performed in a recumbent position. However, a recent preliminary study demonstrated a higher sensitivity of SST when performed in the upright (i.e. seated) position. Here, we report a case of posture-responsive PA with a negative recumbent SST but clea...

Introduction: Worldwide constantly rising incidence of thyroid cancer promotes research activities. Nowadays the most speculated issue is the clinical significance of BRAF mutation. For sure BRAF mutation is a cancer-specific somatic mutation consistent with papillary thyroid cancer phenotype, otherwise, its role in tumor aggressiveness, progression, and the overall poor outcome is controversial. As far as several clinical studies claim opposing opinions, the learning aspect o...

Introduction: Obesity represents a major public health challenge and is linked with increased risk of multiple medical conditions including atrial fibrillation (AF). We have recently published the study protocol of the ‘The Effect of complex weigHt-reducing interventiOns on rhythm control in oBese subjects wITh Atrial Fibrillation’ (HOBIT-AF) trial. Here we communicate the preliminary results with the focus on the use of smart technologies and telemedicine.<...